乌苯美司
Catalog No: 17030602
CAS Number: 58970-76-6
Purity: 98%
Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | 乌苯美司 |
|---|---|
| Iupac Chemical Name | ((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)-L-leucine |
| Synonyms | Ubenimex; NK 421; NK-421; NK421; Bestatin; NSC 265489 |
| Molecular Formula | C16H24N2O4 |
| Molecular Weight | 308.378 |
| Smile | N[C@@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)O)O)CC1=CC=CC=C1 |
| InChiKey | VGGGPCQERPFHOB-RDBSUJKOSA-N |
| InChi | InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 |
| CAS Number | 58970-76-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色至白色固体 |
|---|---|
| Purity | 98% |
| Storage | 短期可在0-4度保存，数天至数月；长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO；不溶于水 |
| Handling | |
| Shipping Condition | 可在常温下运输 |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
