Ubenimex
Catalog No: 17030602
CAS Number: 58970-76-6
Purity: 98%
Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | Ubenimex |
|---|---|
| Iupac Chemical Name | ((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)-L-leucine |
| Synonyms | Ubenimex; NK 421; NK-421; NK421; Bestatin; NSC 265489 |
| Molecular Formula | C16H24N2O4 |
| Molecular Weight | 308.378 |
| Smile | N[C@@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)O)O)CC1=CC=CC=C1 |
| InChiKey | VGGGPCQERPFHOB-RDBSUJKOSA-N |
| InChi | InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 |
| CAS Number | 58970-76-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
