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Ubenimex

Catalog No.: 17030602
Cas No.: 58970-76-6
Purity : 98% 

Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells. 

For research use only. We do not sell to patients.

Chemical Information

NameUbenimex
Iupac Chemical Name((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)-L-leucine 
SynonymsUbenimex; NK 421; NK-421; NK421; Bestatin; NSC 265489 
Molecular FormulaC16H24N2O4 
Molecular Weight308.378 
SmileN[C@@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)O)O)CC1=CC=CC=C1
InChiKeyVGGGPCQERPFHOB-RDBSUJKOSA-N
InChiInChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
CAS Number58970-76-6
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17030602 - Ubenimex | CAS 58970-76-6

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