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URB602

Catalog No.: 17030711
Cas No.: 565460-15-3
Purity : 98% 
17030711 - URB602 | CAS 565460-15-3

Catalog number : 17030711

CAS number : 565460-15-3

Molecular Formula : C19H21NO2 

Molecular Weight : 295.382 

Iupac Chemical Name : cyclohexyl [1,1'-biphenyl]-3-ylcarbamate 

Smile : C1(=CC(=CC=C1)NC(OC1CCCCC1)=O)C1=CC=CC=C1

InChiKey : HHVUFQYJOSFTEH-UHFFFAOYSA-N

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SynonymsURB602; URB-602; URB 602 
Molecular FormulaC19H21NO2 
Molecular Weight295.382 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileC1(=CC(=CC=C1)NC(OC1CCCCC1)=O)C1=CC=CC=C1
InChiKeyHHVUFQYJOSFTEH-UHFFFAOYSA-N
InChiInChI=1S/C19H21NO2/c21-19(22-18-12-5-2-6-13-18)20-17-11-7-10-16(14-17)15-8-3-1-4-9-15/h1,3-4,7-11,14,18H,2,5-6,12-13H2,(H,20,21)
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URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 M for the rat brain enzyme. Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. 

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