UNC0638
Catalog No: 82403
CAS Number: 1255580-76-7
Purity: 98%
UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 treatment of a variety of cell lines resulted in lower global H3K9me2 levels, equivalent to levels observed for small hairpin RNA knockdown of G9a and GLP with the functional potency of UNC0638 being well separated from its toxicity.
For research use only. We do not sell to patients.
Chemical Information
| Name | UNC0638 |
|---|---|
| Iupac Chemical Name | 2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine |
| Synonyms | UNC 0638; UNC-0638 |
| Molecular Formula | C30H47N5O2 |
| Molecular Weight | 509.73 |
| Smile | C1(CCCCC1)C1=NC2=CC(=C(C=C2C(=N1)NC1CCN(CC1)C(C)C)OC)OCCCN1CCCC1 |
| InChiKey | QOECJCJVIMVJGX-UHFFFAOYSA-N |
| InChi | InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33) |
| CAS Number | 1255580-76-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
