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UNC0379

Catalog No: 51801
CAS Number: 1620401-82-2
Purity: 98% 

UNC0379 is a selective, substrate competitive inhibitor of N-lysine methyltransferase SETD8 with IC50 of 7.9 M, high selectivity over 15 other methyltransferases. 

For research use only. We do not sell to patients.

Chemical Information

NameUNC0379
Iupac Chemical Name6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 
SynonymsN/A 
Molecular FormulaC23H35N5O2 
Molecular Weight413.56 
SmileCOC=1C=C2C(=NC(=NC2=CC1OC)N1CCCC1)NCCCCCN1CCCC1
InChiKeyWEXCGGWTIDNVNT-UHFFFAOYSA-N
InChiInChI=1S/C23H35N5O2/c1-29-20-16-18-19(17-21(20)30-2)25-23(28-14-8-9-15-28)26-22(18)24-10-4-3-5-11-27-12-6-7-13-27/h16-17H,3-15H2,1-2H3,(H,24,25,26)
CAS Number1620401-82-2
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Ordering Information

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Formulationwhite solid 
Purity98% 
Storage3 years -20ºCpowder 
Solubility2mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

51801 - UNC0379 | CAS 1620401-82-2

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