UNC0379 is a selective, substrate competitive inhibitor of N-lysine methyltransferase SETD8 with IC50 of 7.9 M, high selectivity over 15 other methyltransferases.
For research use only. We do not sell to patients.
| Name | UNC0379 |
|---|---|
| Iupac Chemical Name | 6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine |
| Synonyms | N/A |
| Molecular Formula | C23H35N5O2 |
| Molecular Weight | 413.56 |
| Smile | COC=1C=C2C(=NC(=NC2=CC1OC)N1CCCC1)NCCCCCN1CCCC1 |
| InChiKey | WEXCGGWTIDNVNT-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H35N5O2/c1-29-20-16-18-19(17-21(20)30-2)25-23(28-14-8-9-15-28)26-22(18)24-10-4-3-5-11-27-12-6-7-13-27/h16-17H,3-15H2,1-2H3,(H,24,25,26) |
| CAS Number | 1620401-82-2 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | 2mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |