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UF-010

Catalog No.: 16122842
Cas No.: 537672-41-6
Purity : 98% 
16122842 - UF-010 | CAS 537672-41-6

Catalog number : 16122842

CAS number : 537672-41-6

Molecular Formula : C11H15BrN2O 

Molecular Weight : 271.158 

Iupac Chemical Name : UF-010 

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SynonymsUF-010; UF 010; UF010 
Molecular FormulaC11H15BrN2O 
Molecular Weight271.158 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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UF-010 is a Class I HDAC inhibitor (IC50 values are 0.06, 0.1, 0.5 and 1.5 M for HDACs 3, 2, 1 and 8, respectively). UF010 inhibits cancer cell proliferation via class I HDAC inhibition. This causes global changes in protein acetylation and gene expression, resulting in activation of tumor suppressor pathways and concurrent inhibition of several oncogenic pathways. The isotype selectivity coupled with interesting biological activities in suppressing tumor cell proliferation support further preclinical development of the UF010 class of compounds for potential therapeutic applications. 

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