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Tropifexor

Catalog No.: 18591
Cas No.: 1383816-29-2
Purity : >98%

Tropifexor, also known as LJN452, is a farnesoid X receptor agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).

For research use only. We do not sell to patients.

Chemical Information

NameTropifexor
Iupac Chemical Name2-[(1R,3r,5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid
SynonymsTropifexor; LJN452; LJN-452; LJN 452.
Molecular FormulaC29H25F4N3O5S
Molecular Weight603.5886
SmileO=C(C1=CC(F)=C2N=C(N3[C@@]4([H])C[C@H](OCC5=C(C6CC6)ON=C5C7=CC=CC=C7OC(F)(F)F)C[C@]3([H])CC4)SC2=C1)O
InChiKeyVYLOOGHLKSNNEK-PIIMJCKOSA-N
InChiInChI=1S/C29H25F4N3O5S/c30-21-9-15(27(37)38)10-23-25(21)34-28(42-23)36-16-7-8-17(36)12-18(11-16)39-13-20-24(35-41-26(20)14-5-6-14)19-3-1-2-4-22(19)40-29(31,32)33/h1-4,9-10,14,16-18H,5-8,11-13H2,(H,37,38)/t16-,17+,18+
CAS Number1383816-29-2
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

18591 - Tropifexor  | CAS 1383816-29-2

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