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Trilaciclib

Catalog No.: 185235
Cas No.: 1374743-00-6
Purity : >98%
185235 - Trilaciclib | CAS 1374743-00-6

Catalog number : 185235

CAS number : 1374743-00-6

Molecular Formula : C24H30N8O

Molecular Weight : 446.559

Iupac Chemical Name : 2'-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one

Smile : O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C)CC6)C=C5)N=C43)CCCCC2

InChiKey : PDGKHKMBHVFCMG-UHFFFAOYSA-N

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SynonymsG1T28; G1T-28; G1T 28; Trilaciclib.
Molecular FormulaC24H30N8O
Molecular Weight446.559
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileO=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C)CC6)C=C5)N=C43)CCCCC2
InChiKeyPDGKHKMBHVFCMG-UHFFFAOYSA-N
InChiInChI=1S/C24H30N8O/c1-30-9-11-31(12-10-30)18-5-6-20(25-15-18)28-23-26-14-17-13-19-22(33)27-16-24(7-3-2-4-8-24)32(19)21(17)29-23/h5-6,13-15H,2-4,7-12,16H2,1H3,(H,27,33)(H,25,26,28,29)
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Trilaciclib is a potential first-in-class short-acting CDK4/6 inhibitor in development to preserve hematopoietic stem cells and enhance immune system function during chemotherapy.

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