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Trichostatin A

Catalog No.: 17031306
Cas No.: 58880-19-6
Purity : 98% 
17031306 - Trichostatin A | CAS 58880-19-6

Catalog number : 17031306

CAS number : 58880-19-6

Molecular Formula : C17H22N2O3 

Molecular Weight : 302.36818 

Iupac Chemical Name : (R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 

Smile : CN(C1=CC=C(C=C1)C([C@@H](/C=C(/C=C/C(=O)NO)\C)C)=O)C

InChiKey : RTKIYFITIVXBLE-QEQCGCAPSA-N

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SynonymsTrichostatin A 
Molecular FormulaC17H22N2O3 
Molecular Weight302.36818 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCN(C1=CC=C(C=C1)C([C@@H](/C=C(/C=C/C(=O)NO)\C)C)=O)C
InChiKeyRTKIYFITIVXBLE-QEQCGCAPSA-N
InChiInChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
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Trichostatin A, also known as TSA, is a HDAC inhibitor. TSA inhibits the eukaryotic cell cycle during the beginning of the growth stage. TSA can be used to alter gene expression by interfering with the removal of acetyl groups from histones (histone deacetylases, HDAC) and therefore altering the ability of DNA transcription factors to access the DNA molecules inside chromatin.

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