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TOVINONTRINE ( IMR-687 )

Catalog No: 218701
CAS Number: 2062661-53-2
Purity: ≧98.0%

TOVINONTRINE ( IMR-687 ) is a highly selective and potent small molecule inhibitor of phosphodiesterase-9 (PDE9). Tovinontrine has a multimodal mechanism of action that acts primarily on red blood cells, or RBCs, and has the potential to act on white blood cells, or WBCs, adhesion mediators and other cell types. 

For research use only. We do not sell to patients.

Chemical Information

NameTOVINONTRINE ( IMR-687 )
Iupac Chemical Name6-{(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl}-3-(oxan-4-yl)imidazo[1,5-a]pyrazin-8(7H)-one
SynonymsIMR-687 ; TOVINONTRINE ; IMR687 ; IMR 687
Molecular FormulaC21H26N6O2
Molecular Weight394.479
SmileO=C1C2=CN=C(C3CCOCC3)N2C=C([C@@H]4CN(CC5=NC=CC=N5)C[C@H]4C)N1
InChiKeyGWGNPYYVGANHRJ-GDBMZVCRSA-N
InChiInChI=1S/C21H26N6O2/c1-14-10-26(13-19-22-5-2-6-23-19)11-16(14)17-12-27-18(21(28)25-17)9-24-20(27)15-3-7-29-8-4-15/h2,5-6,9,12,14-16H,3-4,7-8,10-11,13H2,1H3,(H,25,28)/t14-,16-/m1/s1
CAS Number2062661-53-2
Related CAS2062661-53-2

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-27-65522453   Email : sales@sun-shinechem.com
FormulationOff-white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Coming soon.
TargetsTovinontrine is a phosphodiesterase 9 (PDE9) inhibitor.
Mechanism
Cell studySickle cell
Animal study
Clinical studyPhase 2b
Not available

Chemical Structure

218701 - TOVINONTRINE ( IMR-687 ) | CAS 2062661-53-2

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