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Topotecan

Catalog No.: 1811212
Cas No.: 123948-87-8
Purity : >98%
1811212 - Topotecan | CAS 123948-87-8

Catalog number : 1811212

CAS number : 123948-87-8

Molecular Formula : C23H24ClN3O5

Molecular Weight : 457.91

Iupac Chemical Name : (S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride

Smile : O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl

InChiKey : DGHHQBMTXTWTJV-BQAIUKQQSA-N

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SynonymsNSC 609699 NSC-609699 NSC609699; SKF S104864A. SKF 104864 A SKF-104864-A; SKF104864A; TOPO. Hycamtamine; Hycamtin Hydrochloride; Nogitecan Hydrochloride; Topotecan; Nogitecan Hydrochloride;
Molecular FormulaC23H24ClN3O5
Molecular Weight457.91
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileO=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.[H]Cl
InChiKeyDGHHQBMTXTWTJV-BQAIUKQQSA-N
InChiInChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1
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Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity.

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