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Tipiracil HCl

Catalog No.: 17030710
Cas No.: 183204-72-0
Purity : 98% 

Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally. TAS-102 was approved in Japan in 2015. 

For research use only. We do not sell to patients.

Chemical Information

NameTipiracil HCl
Iupac Chemical Name5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione hydrochloride 
SynonymsTAS-1-462, MA-1; Tipiracil HCl, TPI; TAS-102 
Molecular FormulaC9H12Cl2N4O2 
Molecular Weight279.12318 
SmileCl.ClC=1C(NC(NC1CN1C(CCC1)=N)=O)=O
InChiKeyKGHYQYACJRXCAT-UHFFFAOYSA-N
InChiInChI=1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H
CAS Number183204-72-0
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17030710 - Tipiracil HCl | CAS 183204-72-0

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