Tipiracil HCl
Catalog No: 17030710
CAS Number: 183204-72-0
Purity: 98%
Tipiralacil，又称TPI，是胸腺嘧啶磷酸化酶抑制剂(TPI)。Tipiracil是TAS- 102的活性成分之一，它是目前临床试验中的抗癌药物候选。TAS- 102由细胞毒素三氟吡啶和胸苷磷酸化酶抑制剂(TPI)tipiracil组成。三氟吡啶在DNA合成过程中融入DNA，抑制肿瘤细胞的生长。Tipiracil保护trifluridine在口服时被分解。2015年，TAS- 102在日本获得批准。
For research use only. We do not sell to patients.
Chemical Information
| Name | Tipiracil HCl |
|---|---|
| Iupac Chemical Name | 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione hydrochloride |
| Synonyms | TAS-1-462, MA-1; Tipiracil HCl, TPI; TAS-102 |
| Molecular Formula | C9H12Cl2N4O2 |
| Molecular Weight | 279.12318 |
| Smile | Cl.ClC=1C(NC(NC1CN1C(CCC1)=N)=O)=O |
| InChiKey | KGHYQYACJRXCAT-UHFFFAOYSA-N |
| InChi | InChI=1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H |
| CAS Number | 183204-72-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色至白色固体 |
|---|---|
| Purity | 98% |
| Storage | 短期可在0-4度保存，数天至数月；长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO |
| Handling | |
| Shipping Condition | 可在常温下运输 |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
