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Tinengotinib ( TT-00420)

Catalog No: 20553
CAS Number: 2230490-29-4
Purity: ≧98.0%

Tinengotinib ( TT-00420) is a novel multiple kinase inhibitor that strongly inhibited Aurora A/B, FGFR1/2/3, VEGFRs, JAK1/2, and CSF1R in biochemical assays. Exposure to tinengotinib specifically inhibited proliferation across all subtypes of TNBC (Triple-negative breast cancer) in vitro and in vivo, while leaving luminal breast cancer cells intact.

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Chemical Information

NameTinengotinib ( TT-00420)
Iupac Chemical Name4-(5-(2-chlorophenyl)-3-methyl-1,10-dihydropyrazolo[4,3-b]pyrido[4,3-e][1,4]diazepin-8-yl)morpholine
SynonymsTinengotinib; Tinengotinibum; TT-00420 ; TT 00420 ; TT00420
Molecular FormulaC20H19ClN6O
Molecular Weight394.86
CAS Number2230490-29-4
Related CAS2230490-29-4

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
Request Bulk Quote Download MSDS Tel : +86-177 0271 9238   Email : sales@sun-shinechem.com
FormulationYellow solid
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingRefer to MSDS
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Coming soon.
Targetsmultiple kinase inhibitor
Cell study
Animal study
Clinical study
Not available

Chemical Structure

20553 - Tinengotinib ( TT-00420) | CAS 2230490-29-4

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