TSU-68(SU6668,Orantinib)
Catalog No: 51916
CAS Number: 252916-29-3
Purity: 98%
TSU-68 (SU6668, Orantinib) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR.
For research use only. We do not sell to patients.
Chemical Information
| Name | TSU-68(SU6668,Orantinib) |
|---|---|
| Iupac Chemical Name | (Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid |
| Synonyms | TSU-68,SU6668,Orantinib |
| Molecular Formula | C18H18N2O3 |
| Molecular Weight | 310.35 |
| Smile | CC=1NC(=C(C1CCC(=O)O)C)\C=C\1/C(NC2=CC=CC=C12)=O |
| InChiKey | NHFDRBXTEDBWCZ-ZROIWOOFSA-N |
| InChi | InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9- |
| CAS Number | 252916-29-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | 5mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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