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TPCA-1

Catalog No.: 17031308
Cas No.: 507475-17-4
Purity : 98% 
17031308 - TPCA-1 | CAS 507475-17-4

Catalog number : 17031308

CAS number : 507475-17-4

Molecular Formula : C12H10FN3O2S 

Molecular Weight : 279.29 

Iupac Chemical Name : 5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide 

Smile : FC1=CC=C(C=C1)C1=CC(=C(S1)NC(=O)N)C(=O)N

InChiKey : SAYGKHKXGCPTLX-UHFFFAOYSA-N

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SynonymsTPCA1; TPCA 1; TPCA1 
Molecular FormulaC12H10FN3O2S 
Molecular Weight279.29 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileFC1=CC=C(C=C1)C1=CC(=C(S1)NC(=O)N)C(=O)N
InChiKeySAYGKHKXGCPTLX-UHFFFAOYSA-N
InChiInChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)
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TPCA-1 is a potent IKK-2 inhibitor. TPCA-1 is also an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation in vivo. It selectively repressed proliferation of NSCLC cells with constitutive STAT3 activation.

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