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TP0463518

Catalog No.: 1812282
Cas No.: 1558021-37-0
Purity : >98%
1812282 - TP0463518  | CAS 1558021-37-0

Catalog number : 1812282

CAS number : 1558021-37-0

Molecular Formula : C20H18ClN3O6

Molecular Weight : 431.829

Iupac Chemical Name : (1-((6-(4-chlorophenoxy)pyridin-3-yl)methyl)-4-hydroxy-2-oxo-1,2,5,6-tetrahydropyridine-3-carbonyl)glycine

Smile : O=C(O)CNC(C1=C(O)CCN(CC2=CC=C(OC3=CC=C(Cl)C=C3)N=C2)C1=O)=O

InChiKey : HMMHKGLPKAQOOH-UHFFFAOYSA-N

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SynonymsTP0463518; TP-0463518; TP 0463518;
Molecular FormulaC20H18ClN3O6
Molecular Weight431.829
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileO=C(O)CNC(C1=C(O)CCN(CC2=CC=C(OC3=CC=C(Cl)C=C3)N=C2)C1=O)=O
InChiKeyHMMHKGLPKAQOOH-UHFFFAOYSA-N
InChiInChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)
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TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor. TP0463518 competitively inhibited human PHD2 with a Ki value of 5.3 nM.

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