TNG908
Catalog No: 20646
CAS Number: 2760481-53-4
Purity: ≧98.0%
TNG908 is a clinical stage MTA-cooperative PRMT5 inhibitor that is selectively active in MTAP-deleted cells by leveraging a synthetic lethal interaction.
For research use only. We do not sell to patients.
Chemical Information
| Name | TNG908 |
|---|---|
| Iupac Chemical Name | rel-N-(6-amino-5-methyl-3-pyridyl)-2-[(2R,5S)-2-(1,3-benzothiazol-5-yl)-5-methyl-1-piperidyl]-2-oxoacetamide |
| Synonyms | TNG908 ; TNG 908 ; TNG-908 |
| Molecular Formula | C21H23N5O2S |
| Molecular Weight | 409.51 |
| Smile | O=C(NC1=CC(C)=C(N)N=C1)C(N2[C@@H](C3=CC=C(SC=N4)C4=C3)CC[C@H](C)C2)=O |
| InChiKey | NXXBDYHMHHINFC-YVEFUNNKSA-N |
| InChi | InChI=1S/C21H23N5O2S/c1-12-3-5-17(14-4-6-18-16(8-14)24-11-29-18)26(10-12)21(28)20(27)25-15-7-13(2)19(22)23-9-15/h4,6-9,11-12,17H,3,5,10H2,1-2H3,(H2,22,23)(H,25,27)/t12-,17+/m0/s1 |
| CAS Number | 2760481-53-4 |
| Related CAS | 2760481-53-4 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
