TH287是人7,8-二氢-8-草酸鸟苷三磷酸酶MTH1 (NUDT1)的有效抑制剂,IC50值为5 nM,具有良好的代谢稳定性。
For research use only. We do not sell to patients.
| Name | TH287 |
|---|---|
| Iupac Chemical Name | 6-(2,3-dichlorophenyl)-N4-methylpyrimidine-2,4-diamine |
| Synonyms | TH287; TH 287; TH-287. |
| Molecular Formula | C11H10Cl2N4 |
| Molecular Weight | 269.13 |
| Smile | NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC)=N1 |
| InChiKey | URWCXPXBBITYLR-UHFFFAOYSA-N |
| InChi | InChI=1S/C11H10Cl2N4/c1-15-9-5-8(16-11(14)17-9)6-3-2-4-7(12)10(6)13/h2-5H,1H3,(H3,14,15,16,17) |
| CAS Number | 1609960-30-6 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色至白色固体 |
|---|---|
| Purity | >98% |
| Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO |
| Handling | |
| Shipping Condition | 可在常温下运输 |
| HS Code |
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |