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TH287

Catalog No: 193135
CAS Number: 1609960-30-6
Purity: >98%

TH287 is a potent inhibitor of human 7,8-Dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1) with an IC50 value of 5 nM and good metabolic stability.

For research use only. We do not sell to patients.

Chemical Information

NameTH287
Iupac Chemical Name6-(2,3-dichlorophenyl)-N4-methylpyrimidine-2,4-diamine
SynonymsTH287; TH 287; TH-287.
Molecular FormulaC11H10Cl2N4
Molecular Weight269.13
SmileNC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC)=N1
InChiKeyURWCXPXBBITYLR-UHFFFAOYSA-N
InChiInChI=1S/C11H10Cl2N4/c1-15-9-5-8(16-11(14)17-9)6-3-2-4-7(12)10(6)13/h2-5H,1H3,(H3,14,15,16,17)
CAS Number1609960-30-6
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Ordering Information

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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

193135 - TH287 | CAS 1609960-30-6

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