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TG02 ( SB1317 )

Catalog No.: 62502
Cas No.: 937270-47-8
Purity : ≧98.0%

SB1317 (TG02) is a novel small molecule potent CDK/JAK2/FLT3 inhibitor.  SB1317 was soluble, highly permeable in Caco-2 cells, and showed > 99% binding to plasma from mice, dog and humans. 

For research use only. We do not sell to patients.

Chemical Information

NameTG02 ( SB1317 )
Iupac Chemical Name14-Methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene 
SynonymsTG-02 ; TG 02 ; TG02 ; SB1317; SB-1317 ; SB 1317
Molecular FormulaC23H24N4O 
Molecular Weight372.46 
SmileCN1CC=2C=CC=C(NC=3N=CC=C(C=4C=CC=C(OCCC=CC1)C4)N3)C2
InChiKeyVXBAJLGYBMTJCY-UHFFFAOYSA-N
InChiInChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26)
CAS Number937270-47-8
Related CAS937270-47-8

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO 
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
TargetsCDK/JAK2/FLT3 inhibitor
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

62502 - TG02 ( SB1317 ) | CAS 937270-47-8

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