Fedratinib ( TG-101348 )
Catalog No: 122306
CAS Number: 936091-26-8
Purity: 98%
Fedratinib ( TG-101348 ) is a selective inhibitor of JAK2 with IC50 of 3 nM, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3, TG-101348 also inhibit BRD4 with IC50 of 340 nM.
Fedratinib ( TG-101348 )，contact us by email for the Bulk quotation.
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Chemical Information
| Name | Fedratinib ( TG-101348 ) |
|---|---|
| Iupac Chemical Name | N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide |
| Synonyms | Fedratinib ; SAR 302503 ; TG101348 ; TG 101348 |
| Molecular Formula | C27H36N6O3S |
| Molecular Weight | 524.678 |
| Smile | O=S(C1=CC=CC(NC2=NC(NC3=CC=C(OCCN4CCCC4)C=C3)=NC=C2C)=C1)(NC(C)(C)C)=O |
| InChiKey | JOOXLOJCABQBSG-UHFFFAOYSA-N |
| InChi | InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31) |
| CAS Number | 936091-26-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
