+86-27-65522453 sales@sun-shinechem.com

TAS-103

Catalog No.: 17011718
Cas No.: 174634-08-3
Purity : 98% 
17011718 - TAS-103 | CAS 174634-08-3

Catalog number : 17011718

CAS number : 174634-08-3

Molecular Formula : C20H21Cl2N3O2 

Molecular Weight : 406.31 

Iupac Chemical Name : 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride 

Smile : Cl.Cl.CN(CCNC1=NC2=CC(=CC=C2C2=C1C(C1=CC=CC=C12)=O)O)C

InChiKey : HAYAYGFVSIWSGQ-UHFFFAOYSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsTAS103; TAS-103; TAS 103; BMS247615; BMS 247615; BMS-247615 
Molecular FormulaC20H21Cl2N3O2 
Molecular Weight406.31 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCl.Cl.CN(CCNC1=NC2=CC(=CC=C2C2=C1C(C1=CC=CC=C12)=O)O)C
InChiKeyHAYAYGFVSIWSGQ-UHFFFAOYSA-N
InChiInChI=1S/C20H19N3O2.2ClH/c1-23(2)10-9-21-20-18-17(13-5-3-4-6-14(13)19(18)25)15-8-7-12(24)11-16(15)22-20;;/h3-8,11,24H,9-10H2,1-2H3,(H,21,22);2*1H
Coming soon.
TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS-103 has been reported to be a potent topoisomerase II poison. TAS-103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0.05). The combination with CDDP augmented the antitumor activity of TAS-103 (p<0.05), indicating that CDDP is one of the most potent candidates to be used in combination with TAS-103 . TAS-103 may be useful in the chemotherapy of colorectal cancer. 

174634-08-3 - Request Bulk Quote

×
174634-08-3 - Request Bulk Quote
Change