TAS-103
Catalog No: 17011718
CAS Number: 174634-08-3
Purity: 98%
TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS-103 has been reported to be a potent topoisomerase II poison. TAS-103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0.05). The combination with CDDP augmented the antitumor activity of TAS-103 (p<0.05), indicating that CDDP is one of the most potent candidates to be used in combination with TAS-103 . TAS-103 may be useful in the chemotherapy of colorectal cancer.
For research use only. We do not sell to patients.
Chemical Information
| Name | TAS-103 |
|---|---|
| Iupac Chemical Name | 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride |
| Synonyms | TAS103; TAS-103; TAS 103; BMS247615; BMS 247615; BMS-247615 |
| Molecular Formula | C20H21Cl2N3O2 |
| Molecular Weight | 406.31 |
| Smile | Cl.Cl.CN(CCNC1=NC2=CC(=CC=C2C2=C1C(C1=CC=CC=C12)=O)O)C |
| InChiKey | HAYAYGFVSIWSGQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H19N3O2.2ClH/c1-23(2)10-9-21-20-18-17(13-5-3-4-6-14(13)19(18)25)15-8-7-12(24)11-16(15)22-20;;/h3-8,11,24H,9-10H2,1-2H3,(H,21,22);2*1H |
| CAS Number | 174634-08-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
