TAK-659 HCl
Catalog No: 17011716
CAS Number: 1312691-41-0
Purity: 98%
TAK-659 is an inhibitor of spleen tyrosine kinase (syk), with potential anti-inflammatory, immunomodulating, and antineoplastic activities. Spleen tyrosine kinase inhibitor TAK-659 may inhibit the activity of syk, which abrogates downstream B-cell receptor (BCR) signaling and leads to an inhibition of B-cell activation, chemotaxis, adhesion and proliferation. Note: TAK-659 free base is less stable. This product is supplied as dihydrochloride form.
For research use only. We do not sell to patients.
Chemical Information
| Name | TAK-659 HCl |
|---|---|
| Iupac Chemical Name | 6-(((1R,2S)-2-aminocyclohexyl)amino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one dihydrochloride |
| Synonyms | TAK-659; TAK 659; TAK-659 HCl; TAK659 dihydrochloride |
| Molecular Formula | C17H23Cl2FN6O |
| Molecular Weight | 417.3104 |
| Smile | Cl.Cl.N[C@@H]1[C@@H](CCCC1)NC1=C(C2=C(C(=N1)C=1C=NN(C1)C)C(NC2)=O)F |
| InChiKey | BZSLKYUVNSVQRA-UVDYRLMLSA-N |
| InChi | InChI=1S/C17H21FN6O.2ClH/c1-24-8-9(6-21-24)15-13-10(7-20-17(13)25)14(18)16(23-15)22-12-5-3-2-4-11(12)19;;/h6,8,11-12H,2-5,7,19H2,1H3,(H,20,25)(H,22,23);2*1H/t11-,12+;;/m0../s1 |
| CAS Number | 1312691-41-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
