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Spautin-1

Catalog No.: 102622
Cas No.: 1262888-28-7
Purity : 98% 
102622 - Spautin-1 | CAS 1262888-28-7

Catalog number : 102622

CAS number : 1262888-28-7

Molecular Formula : C15H11F2N3 

Molecular Weight : 271.26 

Chemical Name : Spautin-1

Smile : C1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F

InChiKey : AWIVHRPYFSSVOG-UHFFFAOYSA-N

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Synonyms6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine 
Molecular FormulaC15H11F2N3 
Molecular Weight271.26 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileC1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F
InChiKeyAWIVHRPYFSSVOG-UHFFFAOYSA-N
InChiInChI=1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7,9H,8H2,(H,18,19,20)
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Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03M. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 M. 

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