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Sivelestat (ONO-5046)

Catalog No.: 16122760
Cas No.: 127373-66-4
Purity : 98% 

Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. It almost shows no activity at a range of other proteases. 

For research use only. We do not sell to patients.

Chemical Information

NameSivelestat (ONO-5046)
Iupac Chemical NameSivelestat (ONO-5046) 
SynonymsONO5046, LY544349, EI546 
Molecular FormulaC20H22N2O7S 
Molecular Weight434.46 
SmileCC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(=O)NCC(=O)O
InChiKeyBTGNGJJLZOIYID-UHFFFAOYSA-N
InChiInChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)
CAS Number127373-66-4
MDLMFCD00889071
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122760 - Sivelestat (ONO-5046) | CAS 127373-66-4

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