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Sivelestat (ONO-5046)

Catalog No.: 16122760
Cas No.: 127373-66-4
Purity : 98% 
16122760 - Sivelestat (ONO-5046) | CAS 127373-66-4

Catalog number : 16122760

CAS number : 127373-66-4

Molecular Formula : C20H22N2O7S 

Molecular Weight : 434.46 

Iupac Chemical Name : Sivelestat (ONO-5046) 

Smile : CC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(=O)NCC(=O)O

InChiKey : BTGNGJJLZOIYID-UHFFFAOYSA-N

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SynonymsONO5046, LY544349, EI546 
Molecular FormulaC20H22N2O7S 
Molecular Weight434.46 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(=O)NCC(=O)O
InChiKeyBTGNGJJLZOIYID-UHFFFAOYSA-N
InChiInChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)
MDLMFCD00889071
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Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. It almost shows no activity at a range of other proteases. 

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