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Sirolimus (Rapamycin)

Catalog No.: 161009003
Cas No.: 53123-88-9
Purity : 98% by HPLC
161009003 - Sirolimus (Rapamycin) | CAS 53123-88-9

Catalog number : 161009003

CAS number : 53123-88-9

Molecular Formula : C51H79NO13

Molecular Weight : 914.17

Iupac Chemical Name : (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4] oxaazacyclohentriacontine-1,5,11,28,29 (4H,6H,31H)-pentone

Smile : O[C@H]\1[C@H](C([C@@H](C[C@@H](/C=C/C=C/C=C(/[C@H](C[C@@H]2CC[C@H]([C@](C(C(N3[C@H](C(O[C@@H](CC([C@@H](/C=C1\C)C)=O)[C@@H](C[C@H]1C[C@H]([C@@H](CC1)O)OC)C)=O)CCCC3)=O)=O)(O2)O)C)OC)\C)C)C)=O)OC

InChiKey : QFJCIRLUMZQUOT-HPLJOQBZSA-N

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SynonymsRAPA; RAP; RPM; SLM; AY 22989; AY22989; AY-22989; SILA 9268A; WY090217; WY-090217; WY 090217; C07909; D00753; sirolimus; rapamycin; Rapamune.
Molecular FormulaC51H79NO13
Molecular Weight914.17
AppearanceSolid powder
Purity98% by HPLC
SolubilitySoluble in DMSO
Storage-20 ℃ for 3 years
Shipping ConditionShipped under ambient temperature
SmileO[C@H]\1[C@H](C([C@@H](C[C@@H](/C=C/C=C/C=C(/[C@H](C[C@@H]2CC[C@H]([C@](C(C(N3[C@H](C(O[C@@H](CC([C@@H](/C=C1\C)C)=O)[C@@H](C[C@H]1C[C@H]([C@@H](CC1)O)OC)C)=O)CCCC3)=O)=O)(O2)O)C)OC)\C)C)C)=O)OC
InChiKeyQFJCIRLUMZQUOT-HPLJOQBZSA-N
InChiInChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1
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In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that bin

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