Serlopitant(VPD-737)
Catalog No.: 16082501
Cas No.: 860642-69-9
Purity : 98% by HPLC
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Catalog number : 16082501
CAS number : 860642-69-9
Molecular Formula : C29H28F7NO2
Molecular Weight : 555.5368
Iupac Chemical Name : 3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one
Smile : FC(C=1C=C(C=C(C1)C(F)(F)F)[C@@H](C)O[C@@H]1[C@H]([C@@H]2CN(C[C@H]2CC1)C1=CC(CC1)=O)C1=CC=C(C=C1)F)(F)F
InChiKey : FLNYCRJBCNNHRH-OIYLJQICSA-N
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| Synonyms | VPD-737; VPD737; VPD 737; MK-0594; MK 0594; MK0594 |
|---|---|
| Molecular Formula | C29H28F7NO2 |
| Molecular Weight | 555.5368 |
| Appearance | Solid powder |
| Purity | 98% by HPLC |
| Solubility | Soluble in DMSO, not in water |
| Storage | -20 ºC for 3 years |
| Shipping Condition | Shipped under ambient temperature |
| Smile | FC(C=1C=C(C=C(C1)C(F)(F)F)[C@@H](C)O[C@@H]1[C@H]([C@@H]2CN(C[C@H]2CC1)C1=CC(CC1)=O)C1=CC=C(C=C1)F)(F)F |
| InChiKey | FLNYCRJBCNNHRH-OIYLJQICSA-N |
| InChi | InChI=1S/C29H28F7NO2/c1-16(19-10-20(28(31,32)33)12-21(11-19)29(34,35)36)39-26-9-4-18-14-37(23-7-8-24(38)13-23)15-25(18)27(26)17-2-5-22(30)6-3-17/h2-3,5-6,10-13,16,18,25-27H,4,7-9,14-15H2,1H3/t16-,18-,25-,26+,27+/m1/s1 |
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Serlopitant (VPD-737) is a drug which acts as an NK1 receptor antagonist. It was assessed in clinical trials for the treatment of urinary incontinence and overactive bladder, but while it was superior to placebo it provided no advantage over existing approved drugs, and was not approved for further development.
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