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Serlopitant(VPD-737)

编号: 16082501
Cas号: 860642-69-9
纯度: 98% by HPLC 

Serlopitant (VPD-737) is a drug which acts as an NK1 receptor antagonist. It was assessed in clinical trials for the treatment of urinary incontinence and overactive bladder, but while it was superior to placebo it provided no advantage over existing approved drugs, and was not approved for further development.

 

For research use only. We do not sell to patients.

化学信息

名称Serlopitant(VPD-737)
Iupac 化学名称3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one 
同义词VPD-737; VPD737; VPD 737; MK-0594; MK 0594; MK0594 
分子式C29H28F7NO2 
分子量555.5368 
SmileFC(C=1C=C(C=C(C1)C(F)(F)F)[C@@H](C)O[C@@H]1[C@H]([C@@H]2CN(C[C@H]2CC1)C1=CC(CC1)=O)C1=CC=C(C=C1)F)(F)F
InChiKeyFLNYCRJBCNNHRH-OIYLJQICSA-N
InChiInChI=1S/C29H28F7NO2/c1-16(19-10-20(28(31,32)33)12-21(11-19)29(34,35)36)39-26-9-4-18-14-37(23-7-8-24(38)13-23)15-25(18)27(26)17-2-5-22(30)6-3-17/h2-3,5-6,10-13,16,18,25-27H,4,7-9,14-15H2,1H3/t16-,18-,25-,26+,27+/m1/s1
Cas号860642-69-9
Related CAS

订购信息

Packaging价格Availability纯度Shipping Time
Bulk询价询价询价
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FormulationSolid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO, not in water 
Handling
运输条件Shipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16082501 - Serlopitant(VPD-737) | CAS 860642-69-9

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