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Serlopitant(VPD-737)

Catalog No: 16082501
CAS Number: 860642-69-9
Purity: 98% by HPLC 

Serlopitant (VPD-737) is a drug which acts as an NK1 receptor antagonist. It was assessed in clinical trials for the treatment of urinary incontinence and overactive bladder, but while it was superior to placebo it provided no advantage over existing approved drugs, and was not approved for further development.

 

For research use only. We do not sell to patients.

Chemical Information

NameSerlopitant(VPD-737)
Iupac Chemical Name3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one 
SynonymsVPD-737; VPD737; VPD 737; MK-0594; MK 0594; MK0594 
Molecular FormulaC29H28F7NO2 
Molecular Weight555.5368 
SmileFC(C=1C=C(C=C(C1)C(F)(F)F)[C@@H](C)O[C@@H]1[C@H]([C@@H]2CN(C[C@H]2CC1)C1=CC(CC1)=O)C1=CC=C(C=C1)F)(F)F
InChiKeyFLNYCRJBCNNHRH-OIYLJQICSA-N
InChiInChI=1S/C29H28F7NO2/c1-16(19-10-20(28(31,32)33)12-21(11-19)29(34,35)36)39-26-9-4-18-14-37(23-7-8-24(38)13-23)15-25(18)27(26)17-2-5-22(30)6-3-17/h2-3,5-6,10-13,16,18,25-27H,4,7-9,14-15H2,1H3/t16-,18-,25-,26+,27+/m1/s1
CAS Number860642-69-9
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
Purity98% by HPLC 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO, not in water 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16082501 - Serlopitant(VPD-737) | CAS 860642-69-9

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