Salinosporamide A
Catalog No: 111304
CAS Number: 437742-34-2
Purity: 98%
Salinosporamide A is a novel marine derived proteasome inhibitor which inhibits CT-L, C-L, and T-L proteasome activities in human erythrocyte-derived 20S proteasomes with EC50 of 3.5 nM, 430 nM, 28 nM.
For research use only. We do not sell to patients.
Chemical Information
| Name | Salinosporamide A |
|---|---|
| Iupac Chemical Name | (1S,2R,5R)-2-(2-chloroethyl)-5-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-1-methyl-7-oxa-4-azabicyclo[3.2.0]heptane-3,6-dione |
| Synonyms | NPI-0052; Marizomib |
| Molecular Formula | C15H20ClNO4 |
| Molecular Weight | 313.777 |
| Smile | CC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl |
| InChiKey | NGWSFRIPKNWYAO-UHFFFAOYSA-N |
| InChi | InChI=1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19) |
| CAS Number | 437742-34-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
