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Salinosporamide A

Catalog No.: 111304
Cas No.: 437742-34-2
Purity : 98% 
111304 - Salinosporamide A | CAS 437742-34-2

Catalog number : 111304

CAS number : 437742-34-2

Molecular Formula : C15H20ClNO4 

Molecular Weight : 313.777 

Iupac Chemical Name : (1S,2R,5R)-2-(2-chloroethyl)-5-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-1-methyl-7-oxa-4-azabicyclo[3.2.0]heptane-3,6-dione 

Smile : CC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl

InChiKey : NGWSFRIPKNWYAO-UHFFFAOYSA-N

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SynonymsNPI-0052; Marizomib 
Molecular FormulaC15H20ClNO4 
Molecular Weight313.777 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl
InChiKeyNGWSFRIPKNWYAO-UHFFFAOYSA-N
InChiInChI=1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)
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Salinosporamide A is a novel marine derived proteasome inhibitor which inhibits CT-L, C-L, and T-L proteasome activities in human erythrocyte-derived 20S proteasomes with EC50 of 3.5 nM, 430 nM, 28 nM. 

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