Tersolisib ( STX-478 ) 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
For research use only. We do not sell to patients.
| Name | Tersolisib ( STX-478 ) |
|---|---|
| Iupac Chemical Name | (R)-1-(2-aminopyrimidin-5-yl)-3-(1-(5,7-difluoro-3-methylbenzofuran-2-yl)-2,2,2-trifluoroethyl)urea |
| Synonyms | STX-478 ; STX 478 ; STX478 ; Tersolisib |
| Molecular Formula | C16H12F5N5O2 |
| Molecular Weight | 401.29 |
| Smile | O=C(N[C@H](C1=C(C)C2=CC(F)=CC(F)=C2O1)C(F)(F)F)NC3=CN=C(N)N=C3 |
| InChiKey | LGPNQALKGDDVBD-CYBMUJFWSA-N |
| InChi | InChI=1S/C16H12F5N5O2/c1-6-9-2-7(17)3-10(18)12(9)28-11(6)13(16(19,20)21)26-15(27)25-8-4-23-14(22)24-5-8/h2-5,13H,1H3,(H2,22,23,24)(H2,25,26,27)/t13-/m1/s1 |
| CAS Number | 2883540-92-7 |
| Related CAS | 2883540-92-7 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色固体 |
|---|---|
| Purity | ≧98.0% |
| Storage | 短期(几天到几周)为0-4摄氏度,长期(几个月)为-20摄氏度 |
| Solubility | 溶于DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | 作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周. |
| HS Code | 2934200090 |
| Targets | PI3Kα inhibitor |
|---|---|
| Mechanism | STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteric inhibitor. |
| Cell study | |
| Animal study | |
| Clinical study |