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SRT2104

Catalog No.: 16071014
Cas No.: 1093403-33-8
Purity : 98% by HPLC 
16071014 - SRT2104 | CAS 1093403-33-8

Catalog number : 16071014

CAS number : 1093403-33-8

Molecular Formula : C26H24N6O2S2 

Molecular Weight : 516.64 

Iupac Chemical Name : 4-methyl-N-(2-(3-(morpholinomethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-(pyridin-3-yl)thiazole-5-carboxamide 

Smile : CC=1N=C(SC1C(=O)NC1=C(C=CC=C1)C=1N=C2SC=C(N2C1)CN1CCOCC1)C=1C=NC=CC1

InChiKey : LAMQVIQMVKWXOC-UHFFFAOYSA-N

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SynonymsSRT2104; SRT 2104 
Molecular FormulaC26H24N6O2S2 
Molecular Weight516.64 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCC=1N=C(SC1C(=O)NC1=C(C=CC=C1)C=1N=C2SC=C(N2C1)CN1CCOCC1)C=1C=NC=CC1
InChiKeyLAMQVIQMVKWXOC-UHFFFAOYSA-N
InChiInChI=1S/C26H24N6O2S2/c1-17-23(36-25(28-17)18-5-4-8-27-13-18)24(33)29-21-7-3-2-6-20(21)22-15-32-19(16-35-26(32)30-22)14-31-9-11-34-12-10-31/h2-8,13,15-16H,9-12,14H2,1H3,(H,29,33)
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SRT2104, also known as GSK2245840, is a novel, first-in-class, highly selective small molecule activator of the NAD + dependent deacetylase SIRT1. SRT2104 has been developed as a selective small molecule activator of SIRT1, a NAD(+)-dependent deacetylase involved in the regulation of energy homeostasis and the modulation of various metabolic pathways, including glucose metabolism, oxidative stress and lipid metabolism. SIRT1 has been suggested as putative therapeutic target in multiple age-related diseases including type 2 diabetes and dyslipidemias. 

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