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SRT2104

Catalog No.: 16071014
Cas No.: 1093403-33-8
Purity : 98% by HPLC 

SRT2104, also known as GSK2245840, is a novel, first-in-class, highly selective small molecule activator of the NAD + dependent deacetylase SIRT1. SRT2104 has been developed as a selective small molecule activator of SIRT1, a NAD(+)-dependent deacetylase involved in the regulation of energy homeostasis and the modulation of various metabolic pathways, including glucose metabolism, oxidative stress and lipid metabolism. SIRT1 has been suggested as putative therapeutic target in multiple age-related diseases including type 2 diabetes and dyslipidemias. 

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Chemical Information

NameSRT2104
Iupac Chemical Name4-methyl-N-(2-(3-(morpholinomethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-(pyridin-3-yl)thiazole-5-carboxamide 
SynonymsSRT2104; SRT 2104 
Molecular FormulaC26H24N6O2S2 
Molecular Weight516.64 
SmileCC=1N=C(SC1C(=O)NC1=C(C=CC=C1)C=1N=C2SC=C(N2C1)CN1CCOCC1)C=1C=NC=CC1
InChiKeyLAMQVIQMVKWXOC-UHFFFAOYSA-N
InChiInChI=1S/C26H24N6O2S2/c1-17-23(36-25(28-17)18-5-4-8-27-13-18)24(33)29-21-7-3-2-6-20(21)22-15-32-19(16-35-26(32)30-22)14-31-9-11-34-12-10-31/h2-8,13,15-16H,9-12,14H2,1H3,(H,29,33)
CAS Number1093403-33-8
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Ordering Information

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FormulationSolid powder 
Purity98% by HPLC 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16071014 - SRT2104 | CAS 1093403-33-8

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