SNS-032 has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6.
For research use only. We do not sell to patients.
| Name | SNS-032 ( BMS-387032 ) |
|---|---|
| Iupac Chemical Name | N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide |
| Synonyms | SNS-032 ; BMS-387032 ; SNS032 ; SNS 032 ; BMS 387032 ; BMS387032 |
| Molecular Formula | C17H24N4O2S2 |
| Molecular Weight | 380.53 |
| Smile | C(C)(C)(C)C1=CN=C(O1)CSC1=CN=C(S1)NC(=O)C1CCNCC1 |
| InChiKey | OUSFTKFNBAZUKL-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22) |
| CAS Number | 345627-80-7 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | 5mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |