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SMI-4a

Catalog No.: 52537
Cas No.: 438190-29-5
Purity : 98% 

SMI-4a is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM for Pim-1 compared to an IC50 of 100 nM for Pim-2 and with little or no activity against a panel of 50 other kinases tested 

For research use only. We do not sell to patients.

Chemical Information

NameSMI-4a
Iupac Chemical Name(5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione 
Molecular FormulaC11H6F3NO2S 
Molecular Weight273.23 
SmileO=C(NC/1=O)SC1=C/C2=CC=CC(C(F)(F)F)=C2
InChiKeyNGJLOFCOEOHFKQ-YVMONPNESA-N
InChiInChI=1S/C11H6F3NO2S/c12-11(13,14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17)/b8-5-
CAS Number438190-29-5
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52537 - SMI-4a | CAS 438190-29-5

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