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SJB3-019A

Catalog No.: 611930
Cas No.:
Purity : 98% 
611930 - SJB3-019A

Catalog number : 611930

CAS number :

Molecular Formula : C16H8N2O3 

Molecular Weight : 276.25 

Iupac Chemical Name : SJB3-019A 

Smile : C[Si](C)(C)CSCCl

InChiKey : IKWIERSJEROYFH-UHFFFAOYSA-N

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Molecular FormulaC16H8N2O3 
Molecular Weight276.25 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileC[Si](C)(C)CSCCl
InChiKeyIKWIERSJEROYFH-UHFFFAOYSA-N
InChiInChI=1S/C5H13ClSSi/c1-8(2,3)5-7-4-6/h4-5H2,1-3H3
MDLMFCD17013410
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SJB3-019A is a potent and novel usp1 inhibitor. SJB3-019A (IC50 = 0.0781 uM) was 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells.

SJB3-019A also increased the levels of Ub-FANCD2 and Ub-PCNA, and decreased the HR activity .

 

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