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SEA0400

Catalog No.: 16070911
Cas No.: 223104-29-8
Purity : 98% by HPLC 
16070911 - SEA0400 | CAS 223104-29-8

Catalog number : 16070911

CAS number : 223104-29-8

Molecular Formula : C21H19F2NO3 

Molecular Weight : 371.3838 

Iupac Chemical Name : 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline 

Smile : FC1=C(C=C(C=C1)F)COC1=CC=C(OC2=C(N)C=C(C=C2)OCC)C=C1

InChiKey : YSUBLPUJDOWYDP-UHFFFAOYSA-N

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SynonymsC21H19F2NO3 
Molecular FormulaC21H19F2NO3 
Molecular Weight371.3838 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileFC1=C(C=C(C=C1)F)COC1=CC=C(OC2=C(N)C=C(C=C2)OCC)C=C1
InChiKeyYSUBLPUJDOWYDP-UHFFFAOYSA-N
InChiInChI=1S/C21H19F2NO3/c1-2-25-18-8-10-21(20(24)12-18)27-17-6-4-16(5-7-17)26-13-14-11-15(22)3-9-19(14)23/h3-12H,2,13,24H2,1H3
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SEA0400 is a Na+/Ca2+ exchanger 1 inhibitor. SEA0400 prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. SEA0400 reduces calcium overload induced by ischemia and reperfusion in mouse ventricular myocytes. SEA0400 attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia. SEA0400, preserves cardiac function and high-energy phosphates against ischemia/reperfusion injury. 

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