SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM, 100-fold more selective for ALK5 than p38 MAPK and other kinases.
For research use only. We do not sell to patients.
| Name | SB431542 |
|---|---|
| Iupac Chemical Name | 4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide |
| Synonyms | N/A |
| Molecular Formula | C22H16N4O3 |
| Molecular Weight | 384.39 |
| Smile | O1COC2=C1C=CC(=C2)C=2N=C(NC2C2=NC=CC=C2)C2=CC=C(C(=O)N)C=C2 |
| InChiKey | FHYUGAJXYORMHI-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26) |
| CAS Number | 301836-41-9 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Handling | |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |