SB-216763
Catalog No: 161009026
CAS Number: 280744-09-4
Purity: 98% by HPLC
SB-216763 is a glycogen synthase kinase-3 (GSK3) inhibitor, which can maintain mouse embryonic stem cells (mESCs) in a pluripotent state in the absence of exogenous leukemia inhibitory factor (LIF) when cultured on mouse embryonic fibroblasts (MEFs). SB-216763 is the first GSK3 inhibitor that can promote self-renewal of mESC co-cultured with MEFs for more than two months.
For research use only. We do not sell to patients.
Chemical Information
| Name | SB-216763 |
|---|---|
| Iupac Chemical Name | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Synonyms | SB216763; SB 216763; SB216763 |
| Molecular Formula | C19H12Cl2N2O2 |
| Molecular Weight | 371.22 |
| Smile | ClC1=C(C=CC(=C1)Cl)C=1C(NC(C1C1=CN(C2=CC=CC=C12)C)=O)=O |
| InChiKey | JCSGFHVFHSKIJH-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25) |
| CAS Number | 280744-09-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
