Roginolisib
Catalog No: 25068
CAS Number: 1305267-37-1
Purity: 98% Min.
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and selective PI3Kδ inhibitor that shows high selective against a panel of 278 additional kinases.
For research use only. We do not sell to patients.
Chemical Information
| Name | Roginolisib |
|---|---|
| Iupac Chemical Name | (6-fluoro-1-(4-(morpholinomethyl)phenyl)-5,5-dioxido-1,4-dihydrothiochromeno[4,3-c]pyrazol-3-yl)(morpholino)methanone |
| Synonyms | MSC2360844; MSC 2360844; MSC-2360844, roginolisib; IOA-244; IOA 244; IOA244; |
| Molecular Formula | C26H27FN4O5S |
| Molecular Weight | 526.58 |
| Smile | O=C(C1=NN(C2=CC=C(CN3CCOCC3)C=C2)C(C4=CC=CC(F)=C45)=C1CS5(=O)=O)N6CCOCC6 |
| InChiKey | NFHSJYKXENYICE-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H27FN4O5S/c27-22-3-1-2-20-24-21(17-37(33,34)25(20)22)23(26(32)30-10-14-36-15-11-30)28-31(24)19-6-4-18(5-7-19)16-29-8-12-35-13-9-29/h1-7H,8-17H2 |
| CAS Number | 1305267-37-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Haselmayer P, et al. Characterization of Novel PI3Kδ Inhibitors as Potential Therapeutics for SLE and Lupus Nephritis in Pre-Clinical Studies. Front Immunol. 2014 May 22;5:233.
Chemical Structure
