Rocilinostat (ACY-1215)
编号: 52104
Cas号: 1316214-52-4
纯度: 98%
Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. Phase 2.
For research use only. We do not sell to patients.
化学信息
| 名称 | Rocilinostat (ACY-1215) |
|---|---|
| Iupac 化学名称 | 5-Pyrimidinecarboxamide, 2-(diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]- |
| 同义词 | Rocilinostat,ACY-1215 |
| 分子式 | C24H27N5O3 |
| 分子量 | 433.5 |
| Smile | C1(=CC=CC=C1)N(C1=NC=C(C=N1)C(=O)NCCCCCCC(=O)NO)C1=CC=CC=C1 |
| InChiKey | QGZYDVAGYRLSKP-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H27N5O3/c30-22(28-32)15-9-1-2-10-16-25-23(31)19-17-26-24(27-18-19)29(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,17-18,32H,1-2,9-10,15-16H2,(H,25,31)(H,28,30) |
| Cas号 | 1316214-52-4 |
| Related CAS |
订购信息
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| Bulk | 询价 | 询价 | 询价 |
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