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Ro3280

Catalog No.: 52826
Cas No.: 1062243-51-9
Purity : 98% 
52826 - Ro3280 | CAS 1062243-51-9

Catalog number : 52826

CAS number : 1062243-51-9

Molecular Formula : C27H35F2N7O3 

Molecular Weight : 543.61 

Chemical Name : Ro3280

Smile : CN1CCC(CC1)NC(=O)c2ccc(c(c2)OC)Nc3ncc4c(n3)N(CC(C(=O)N4C)(F)F)C5CCCC5

InChiKey : DJNZZLZKAXGMMC-UHFFFAOYSA-N

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Molecular FormulaC27H35F2N7O3 
Molecular Weight543.61 
Purity98% 
SmileCN1CCC(CC1)NC(=O)c2ccc(c(c2)OC)Nc3ncc4c(n3)N(CC(C(=O)N4C)(F)F)C5CCCC5
InChiKeyDJNZZLZKAXGMMC-UHFFFAOYSA-N
InChiInChI=1S/C27H35F2N7O3/c1-34-12-10-18(11-13-34)31-24(37)17-8-9-20(22(14-17)39-3)32-26-30-15-21-23(33-26)36(19-6-4-5-7-19)16-27(28,29)25(38)35(21)2/h8-9,14-15,18-19H,4-7,10-13,16H2,1-3H3,(H,31,37)(H,30,32,33)
MDLMFCD22665717
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RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM. 

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