Ro 5126766
Catalog No.: 010812
Cas No.: 946128-88-7
Purity : 98%
Catalog number : 010812
CAS number : 946128-88-7
Molecular Formula : C21H18FN5O5S
Molecular Weight : 471.462
Chemical Name : Ro 5126766
Smile : CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F
InChiKey : LMMJFBMMJUMSJS-UHFFFAOYSA-N
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| Synonyms | Ro5126766; Ro 5126766; CH-5126766; CH5126766; CH 5126766 |
|---|---|
| Molecular Formula | C21H18FN5O5S |
| Molecular Weight | 471.462 |
| Appearance | Solid powder |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Storage | -20 ºC for 3 years |
| Shipping Condition | Shipped under ambient temperature |
| Smile | CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F |
| InChiKey | LMMJFBMMJUMSJS-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H18FN5O5S/c1-12-15-5-4-14(31-21-25-7-3-8-26-21)11-17(15)32-20(28)16(12)10-13-6-9-24-19(18(13)22)27-33(29,30)23-2/h3-9,11,23H,10H2,1-2H3,(H,24,27) |
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Ro 5126766 is a potent and selective dual RAF/MEK inhibitor. For SK-MEL-28, SK-MEL-2, MIAPaCa-2, and SW480 cell lines, the IC50 is determined by WST-8 assay is 65, 28, 40, and 46 nM, respectively.
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