Rilzabrutinib ( PRN1008 ) is an oral, reversible, covalent, small-molecule inhibitor of Bruton’s tyrosine kinase (BTK).
For research use only. We do not sell to patients.
Name | Rilzabrutinib ( PRN1008 ) |
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Iupac Chemical Name | 2-[(3R)-3-[4-Amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile |
Synonyms | Rilzabrutinib ; PRN1008 ; PRN 1008 ; PRN-1008 |
Molecular Formula | C36H40FN9O3 |
Molecular Weight | 665.77 |
Smile | CC(N1CCN(C2COC2)CC1)(C)C=C(C(N3C[C@H](N4N=C(C5=CC=C(OC6=CC=CC=C6)C=C5F)C7=C(N)N=CN=C74)CCC3)=O)C#N |
InChiKey | LCFFREMLXLZNHE-RUZDIDTESA-N |
InChi | InChI=1S/C36H40FN9O3/c1-36(2,45-15-13-43(14-16-45)26-21-48-22-26)18-24(19-38)35(47)44-12-6-7-25(20-44)46-34-31(33(39)40-23-41-34)32(42-46)29-11-10-28(17-30(29)37)49-27-8-4-3-5-9-27/h3-5,8-11,17-18,23,25-26H,6-7,12-16,20-22H2,1-2H3,(H2,39,40,41)/t25-/m1/s1 |
CAS Number | 1575591-66-0 |
Related CAS | 1575591-66-0 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |