Ranosidenib, also known as HMPL-306, is an isocitrate dehydrogenase (IDH) inhibitor.
For research use only. We do not sell to patients.
| Name | Ranosidenib |
|---|---|
| Iupac Chemical Name | (S)-3-(4,6-bis(((R)-1,1,1-trifluoropropan-2-yl)amino)-1,3,5-triazin-2-yl)-2,6,6-trifluorocyclohex-2-en-1-ol |
| Synonyms | HMPL-306 ; HMPL 306 ; HMPL306 |
| Molecular Formula | C15H16F9N5O |
| Molecular Weight | 453.31 |
| Smile | O[C@H]1C(F)=C(C2=NC(N[C@H](C)C(F)(F)F)=NC(N[C@H](C)C(F)(F)F)=N2)CCC1(F)F |
| InChiKey | CECMHVJGNAFHKN-KCRUCZTKSA-N |
| InChi | InChI=1S/C15H16F9N5O/c1-5(14(19,20)21)25-11-27-10(7-3-4-13(17,18)9(30)8(7)16)28-12(29-11)26-6(2)15(22,23)24/h5-6,9,30H,3-4H2,1-2H3,(H2,25,26,27,28,29)/t5-,6-,9+/m1/s1 |
| CAS Number | 2301974-60-5 |
| Related CAS | 2301974-60-5 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |