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Pamapimod (R-1503, Ro4402257)

Catalog No.: 16122774
Cas No.: 449811-01-2
Purity : 98% 
16122774 - Pamapimod (R-1503, Ro4402257) | CAS 449811-01-2

Catalog number : 16122774

CAS number : 449811-01-2

Molecular Formula : C19H20F2N4O4 

Molecular Weight : 406.38 

Iupac Chemical Name : Pamapimod (R-1503, Ro4402257) 

Smile : CC(C(CCO)Nc1ncc2cc(c(=O)n(c2n1)C)Oc3ccc(cc3F)F)O

InChiKey : RGINMGDUOJVOTG-UHFFFAOYSA-N

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SynonymsN/A 
Molecular FormulaC19H20F2N4O4 
Molecular Weight406.38 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCC(C(CCO)Nc1ncc2cc(c(=O)n(c2n1)C)Oc3ccc(cc3F)F)O
InChiKeyRGINMGDUOJVOTG-UHFFFAOYSA-N
InChiInChI=1S/C19H20F2N4O4/c1-10(27)14(5-6-26)23-19-22-9-11-7-16(18(28)25(2)17(11)24-19)29-15-4-3-12(20)8-13(15)21/h3-4,7-10,14,26-27H,5-6H2,1-2H3,(H,22,23,24)
MDLMFCD14105621
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Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38 and p38 enzymatic activity with IC50 values of 0.0140.002 and 0.48 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms. 

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