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Pamapimod (R-1503, Ro4402257)

Catalog No: 16122774
CAS Number: 449811-01-2
Purity: 98% 

Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38 and p38 enzymatic activity with IC50 values of 0.0140.002 and 0.48 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms. 

For research use only. We do not sell to patients.

Chemical Information

NamePamapimod (R-1503, Ro4402257)
Iupac Chemical NamePamapimod (R-1503, Ro4402257) 
SynonymsN/A 
Molecular FormulaC19H20F2N4O4 
Molecular Weight406.38 
SmileCC(C(CCO)Nc1ncc2cc(c(=O)n(c2n1)C)Oc3ccc(cc3F)F)O
InChiKeyRGINMGDUOJVOTG-UHFFFAOYSA-N
InChiInChI=1S/C19H20F2N4O4/c1-10(27)14(5-6-26)23-19-22-9-11-7-16(18(28)25(2)17(11)24-19)29-15-4-3-12(20)8-13(15)21/h3-4,7-10,14,26-27H,5-6H2,1-2H3,(H,22,23,24)
CAS Number449811-01-2
MDLMFCD14105621
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122774 - Pamapimod (R-1503, Ro4402257) | CAS 449811-01-2

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