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PS 48

Catalog No.: 16071111
Cas No.: 1180676-32-7
Purity : 98% by HPLC 
16071111 - PS 48 | CAS 1180676-32-7

Catalog number : 16071111

CAS number : 1180676-32-7

Molecular Formula : C17H15ClO2 

Molecular Weight : 286.76 

Iupac Chemical Name : (Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid 

Smile : ClC1=CC=C(C=C1)CC/C(=C/C(=O)O)/C1=CC=CC=C1

InChiKey : LLJYFDRQFPQGNY-QINSGFPZSA-N

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Synonyms(Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid 
Molecular FormulaC17H15ClO2 
Molecular Weight286.76 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileClC1=CC=C(C=C1)CC/C(=C/C(=O)O)/C1=CC=CC=C1
InChiKeyLLJYFDRQFPQGNY-QINSGFPZSA-N
InChiInChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
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PS 48 has been shown to be a PKB Kinase (phosphoinositide-dependent protein kinase-1, PDK1) activator (Kd = 10.3 M). Studies have indicated that this compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1). This is a distinct region separate from the ATP binding site. 

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