PHA-767491, also known as CAY10572, is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.
For research use only. We do not sell to patients.
| Name | PHA-767491 HCl |
|---|---|
| Iupac Chemical Name | 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4 H -pyrrolo[3,2- c ]pyridin-4-one hydrochloride |
| Synonyms | PHA767491; PHA-767491; PHA 767491; CAY10572; CAY-10572; CAY 10572. |
| Molecular Formula | C12H12ClN3O |
| Molecular Weight | 249.7 |
| Smile | O=C1C2=C(NC(C3=CC=NC=C3)=C2)CCN1.[H]Cl |
| InChiKey | IMVNFURYBZMFDZ-UHFFFAOYSA-N |
| InChi | InChI=1S/C12H11N3O.ClH/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12;/h1-2,4-5,7,15H,3,6H2,(H,14,16);1H |
| CAS Number | 942425-68-5 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |