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PFI-2 hydrochloride

Catalog No.: 184106
Cas No.: 1627607-87-7
Purity : >98%

PFI-2 is a potent inhibitor of SETD7 with IC50 2 nM and 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.

For research use only. We do not sell to patients.

Chemical Information

NamePFI-2 hydrochloride
Iupac Chemical Name(R)-8-fluoro-N-(1-oxo-1-(pyrrolidin-1-yl)-3-(3-(trifluoromethyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide hydrochloride
SynonymsPFI-2; PFI2; PFI 2; (R)-PFI-2; (R)-PFI-2 hydrochloride. PFI-2 hydrochloride
Molecular FormulaC23H26ClF4N3O3S
Molecular Weight535.98
SmileO=S(C1=CC2=C(CNCC2)C(F)=C1)(N[C@H](CC3=CC=CC(C(F)(F)F)=C3)C(N4CCCC4)=O)=O.[H]Cl
InChiKeyZADKZNVAJGEFLC-ZMBIFBSDSA-N
InChiInChI=1S/C23H25F4N3O3S.ClH/c24-20-13-18(12-16-6-7-28-14-19(16)20)34(32,33)29-21(22(31)30-8-1-2-9-30)11-15-4-3-5-17(10-15)23(25,26)27;/h3-5,10,12-13,21,28-29H,1-2,6-9,11,14H2;1H/t21-;/m1./s1
CAS Number1627607-87-7
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

184106 - PFI-2 hydrochloride | CAS 1627607-87-7

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