PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50 0.08 nM).
For research use only. We do not sell to patients.
| Name | PD 158780 | 
|---|---|
| Iupac Chemical Name | 4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine | 
| Synonyms | PD 158780; PD158780; PD-158780. | 
| Molecular Formula | C14H12BrN5 | 
| Molecular Weight | 330.19 | 
| Smile | CNC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=N1 | 
| InChiKey | KFHMLBXBRCITHF-UHFFFAOYSA-N | 
| InChi | InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20) | 
| CAS Number | 171179-06-9 | 
| Related CAS | 
| Packaging | Price | Availability | Purity | Shipping Time | 
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry | 
| Formulation | off-white solid | 
|---|---|
| Purity | >98% | 
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). | 
| Solubility | Soluble in DMSO | 
| Handling | |
| Shipping Condition | Shipped under ambient temperature | 
| HS Code | 
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | 
