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PD 158780

Catalog No.: 184284
Cas No.: 171179-06-9
Purity : >98%
184284 - PD 158780  | CAS 171179-06-9

Catalog number : 184284

CAS number : 171179-06-9

Molecular Formula : C14H12BrN5

Molecular Weight : 330.19

Iupac Chemical Name : 4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine

Smile : CNC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=N1

InChiKey : KFHMLBXBRCITHF-UHFFFAOYSA-N

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SynonymsPD 158780; PD158780; PD-158780.
Molecular FormulaC14H12BrN5
Molecular Weight330.19
Appearanceoff-white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Smile CNC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=N1
InChiKeyKFHMLBXBRCITHF-UHFFFAOYSA-N
InChiInChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
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PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50 0.08 nM).

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