Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium channels (KCNQ2/3), which are found in several regions of the brain, showing minimal activation of GABA(A) receptors.
For research use only. We do not sell to patients.
| Name | Opakalim |
|---|---|
| Iupac Chemical Name | N-(1-(tert-butyl)-6-cyano-4,7-difluoro-1H-benzo[d]imidazol-2-yl)-3,3-dimethylbutanamide |
| Synonyms | Opakalim ; BHV-7000 ; BHV 7000 ; BHV7000 |
| Molecular Formula | C18H22F2N4O |
| Molecular Weight | 348.40 |
| Smile | FC1=C2C(N=C(NC(CC(C)(C)C)=O)N2C(C)(C)C)=C(F)C=C1C#N |
| InChiKey | VOPRSHDHZUHPBT-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H22F2N4O/c1-17(2,3)8-12(25)22-16-23-14-11(19)7-10(9-21)13(20)15(14)24(16)18(4,5)6/h7H,8H2,1-6H3,(H,22,23,25) |
| CAS Number | 2376397-93-0 |
| Related CAS | 2376397-93-0 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |