Omipalisib(GSK2126458,GSK458)
Catalog No: 121429
CAS Number: 1086062-66-9
Purity: 98%
GSK2126458 is a highly selective and potent inhibitor of PI3K with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/2 , respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | Omipalisib(GSK2126458,GSK458) |
|---|---|
| Iupac Chemical Name | 2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide |
| Synonyms | Omipalisib;GSK-458;GSK-2126458;GSK458;GSK 2126458 |
| Molecular Formula | C25H17F2N5O3S |
| Molecular Weight | 505.496 |
| Smile | FC1=C(C=CC(=C1)F)S(=O)(=O)NC=1C(=NC=C(C1)C=1C=C2C(=CC=NC2=CC1)C1=CN=NC=C1)OC |
| InChiKey | CGBJSGAELGCMKE-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H17F2N5O3S/c1-35-25-23(32-36(33,34)24-5-3-18(26)12-21(24)27)11-17(13-29-25)15-2-4-22-20(10-15)19(7-8-28-22)16-6-9-30-31-14-16/h2-14,32H,1H3 |
| CAS Number | 1086062-66-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ℃ for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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