Ofirnoflast
Catalog No: 26A007
CAS Number: 2731294-23-6
Purity: ≧98.0%
Ofirnoflast is a first-in-class, orally bioavailable NEK7 inhibitor.
For research use only. We do not sell to patients.
Chemical Information
| Name | Ofirnoflast |
|---|---|
| Iupac Chemical Name | N-[4-(4-Amino-7-cyclopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-N'-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea |
| Synonyms | Ofirnoflast ; HT-6184 ; HT6184 ; HT 6184 |
| Molecular Formula | C23H19F4N7O2 |
| Molecular Weight | 501.15 |
| Smile | O=C(NC1=NOC(C2(C(F)(F)F)CC2)=C1)NC3=CC=C(C4=CN(C5CC5)C6=NC=NC(N)=C64)C=C3F |
| InChiKey | MJUUWYZZPRAKCW-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H19F4N7O2/c24-14-7-11(13-9-34(12-2-3-12)20-18(13)19(28)29-10-30-20)1-4-15(14)31-21(35)32-17-8-16(36-33-17)22(5-6-22)23(25,26)27/h1,4,7-10,12H,2-3,5-6H2,(H2,28,29,30)(H2,31,32,33,35) |
| CAS Number | 2731294-23-6 |
| Related CAS | 2731294-23-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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