奥巴克拉对Bcl-xL细胞系中的缺乏表现出较低敏感。在 Mcl-1, Bcl-2,和Bcl-xL细胞系中,具有强烈的表达,并显示了较低的细胞毒性。
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Chemical Information
| Name | 奥巴克拉 |
| Iupac Chemical Name | Obatoclax |
| Synonyms | Obatoclax Mesylate; GX15-070 |
| Molecular Formula | C₂₁H₂₃N₃O₄S |
| Molecular Weight | 413.49 |
| Smile | Cc1cc([nH]c1/C=C\2/C(=CC(=N2)c3cc4ccccc4[nH]3)OC)C.CS(=O)(=O)O |
| InChiKey | ZFKXDVMHNXPEIY-PEZBNFGJSA-N |
| InChi | InChI=1S/C20H19N3O.CH4O3S/c1-12-8-13(2)21-16(12)10-19-20(24-3)11-18(23-19)17-9-14-6-4-5-7-15(14)22-17;1-5(2,3)4/h4-11,21-22H,1-3H3;1H3,(H,2,3,4)/b19-10-; |
| CAS Number | 803712-79-0 |
| MDL | MFCD18074508 |
| Related CAS | |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
| Bulk | | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色至白色固体 |
| Purity | 98% |
| Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO |
| Handling | |
| Shipping Condition | 可在常温下运输 |
| HS Code | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |